Endocrine Abstracts

Polyglandular autoimmune syndrome (PAS) is characterised by the coexistence of two or more autoimmune mediated disorders. While the pathophysiology remains poorly understood, environmental triggers and genetic susceptibility are thought to contribute to the dysregulated immune response. PAS has been classified into three main subgroups: Type 1 is seen in the paediatric population while types 2 and 3 are found in adults with autoimmune thyroid disease and insulin-requiring diab...